Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis

Primary skin tumors are certainly more frequent than metastatic tumors, but the latter can sometimes be the first sign of otherwise unrecognized neoplastic pathology and always correspond to an advanced stage of the disease. Among the various neoplasms that can metastasize in cutaneous districts, sk...

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Main Authors:	Gerardo Cazzato, Anna Colagrande, Antonietta Cimmino, Aurora De Marco, Paolo Romita, Caterina Foti, Leonardo Resta, Giuseppe Ingravallo
Format:	Article
Language:	English
Published:	MDPI AG 2021-06-01
Series:	Life
Subjects:	skin metastasis hepatocarcinoma cholangiocarcinoma metastatic cancer dermopathology
Online Access:	https://www.mdpi.com/2075-1729/11/6/559

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spelling	doaj-2d9914dc0201427abd92f9e3fbfb15ca2021-07-01T00:08:28ZengMDPI AGLife2075-17292021-06-011155955910.3390/life11060559Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential DiagnosisGerardo Cazzato0Anna Colagrande1Antonietta Cimmino2Aurora De Marco3Paolo Romita4Caterina Foti5Leonardo Resta6Giuseppe Ingravallo7Section of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Sciences and Human Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Sciences and Human Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Dermatology, Department of Biomedical Sciences and Human Oncology, University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalySection of Pathology, Department of Emergency and Organ Transplantation (DETO), University of Bari “Aldo Moro”, 70124 Bari, ItalyPrimary skin tumors are certainly more frequent than metastatic tumors, but the latter can sometimes be the first sign of otherwise unrecognized neoplastic pathology and always correspond to an advanced stage of the disease. Among the various neoplasms that can metastasize in cutaneous districts, skin metastases from primary malignant neoplasms from the liver and biliary tract are infrequent, and when they do occur they can pose differential diagnosis problems to the pathologist. Here we present two cases of metastatic skin lesions, respectively originating from the liver and the intrahepatic biliary tract, and we conduct a brief review of the current literature.https://www.mdpi.com/2075-1729/11/6/559skin metastasishepatocarcinomacholangiocarcinomametastaticcancerdermopathology
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Gerardo Cazzato Anna Colagrande Antonietta Cimmino Aurora De Marco Paolo Romita Caterina Foti Leonardo Resta Giuseppe Ingravallo
spellingShingle	Gerardo Cazzato Anna Colagrande Antonietta Cimmino Aurora De Marco Paolo Romita Caterina Foti Leonardo Resta Giuseppe Ingravallo Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis Life skin metastasis hepatocarcinoma cholangiocarcinoma metastatic cancer dermopathology
author_facet	Gerardo Cazzato Anna Colagrande Antonietta Cimmino Aurora De Marco Paolo Romita Caterina Foti Leonardo Resta Giuseppe Ingravallo
author_sort	Gerardo Cazzato
title	Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis
title_short	Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis
title_full	Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis
title_fullStr	Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis
title_full_unstemmed	Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis
title_sort	cutaneous metastases from primary liver cancers: the need for knowledge and differential diagnosis
publisher	MDPI AG
series	Life
issn	2075-1729
publishDate	2021-06-01
description	Primary skin tumors are certainly more frequent than metastatic tumors, but the latter can sometimes be the first sign of otherwise unrecognized neoplastic pathology and always correspond to an advanced stage of the disease. Among the various neoplasms that can metastasize in cutaneous districts, skin metastases from primary malignant neoplasms from the liver and biliary tract are infrequent, and when they do occur they can pose differential diagnosis problems to the pathologist. Here we present two cases of metastatic skin lesions, respectively originating from the liver and the intrahepatic biliary tract, and we conduct a brief review of the current literature.
topic	skin metastasis hepatocarcinoma cholangiocarcinoma metastatic cancer dermopathology
url	https://www.mdpi.com/2075-1729/11/6/559
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Cutaneous Metastases from Primary Liver Cancers: The Need for Knowledge and Differential Diagnosis

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