Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta

Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta

It is widely accepted that diabetes mellitus impairs placental development, but the mechanism by which the disease operates to impair development remains controversial. In this study, we demonstrated that pregestational diabetes mellitus (PGDM)-induced defects in placental development in mice are ma...

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Bibliographic Details
Main Authors: Mei-yao He, Guang Wang, Sha-sha Han, Ya Jin, He Li, Xia Wu, Zheng-lai Ma, Xin cheng, Xiuwen Tang, Xuesong Yang, Guo-sheng Liu
Format: Article
Language:English
Published: The Royal Society 2016-01-01
Series:Open Biology
Subjects:
pregestational diabetes mellitus
placenta
trophoblast cell
ros
nrf2
autophagy
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.160064

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