A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

A muscle-epidermis-glia signaling axis sustains synaptic specificity during allometric growth in Caenorhabditis elegans

Synaptic positions underlie precise circuit connectivity. Synaptic positions can be established during embryogenesis and sustained during growth. The mechanisms that sustain synaptic specificity during allometric growth are largely unknown. We performed forward genetic screens in C. elegans for regu...

Full description

Bibliographic Details
Main Authors: Jiale Fan, Tingting Ji, Kai Wang, Jichang Huang, Mengqing Wang, Laura Manning, Xiaohua Dong, Yanjun Shi, Xumin Zhang, Zhiyong Shao, Daniel A Colón-Ramos
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-04-01
Series:eLife
Subjects:
synaptic allometry
synaptic specificity
adamts family protease
MIG-17
extracellular matrix
glia
Online Access:https://elifesciences.org/articles/55890

Similar Items

Similar Items