MECHANISMS OF CYTOKINE STORM DEVELOPMENT IN COVID-19 AND NEW POTENTIAL TARGETS OF PHARMACOTHERAPY

MECHANISMS OF CYTOKINE STORM DEVELOPMENT IN COVID-19 AND NEW POTENTIAL TARGETS OF PHARMACOTHERAPY

The development of a "cytokine storm", characteristic of severe COVID-19 forms, can be defined as a state of uncontrolled release of a large number of inflammatory mediators.The attachment of SARS-CoV-2 S-glycoprotein to angiotensin-converting enzyme 2 is considered a process that triggers...

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Bibliographic Details
Main Authors: V. I. Petrov, A. A. Amosov, A. S. Gerasimenko, O. V. Shatalova, A. V. Ponomareva, A. N. Akinchits, I. S. Kulakova, V. S. Gorbatenko
Format: Article
Language:Russian
Published: Pyatigorsk Medical and Pharmaceutical Institute - branch of Volgograd State Medical University 2021-05-01
Series:Farmaciâ i Farmakologiâ (Pâtigorsk)
Subjects:
sars-cov-2
"cytokine storm", pharmacotherapy for covid-19
Online Access:https://www.pharmpharm.ru/jour/article/view/767

Internet

https://www.pharmpharm.ru/jour/article/view/767

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