Synthesis and biological evaluation of novel quinazolin-4(3H)-one Schiff base derivatives as nitric oxide synthase inhibitors
Synthesis of new Schiff base derivatives bearing a 6-nitro-2-ibuprofenyl-4(3H)-quinazolin-4-one skeleton, as well as their in vitro biological evaluation as inhibitors of nitric oxide synthase (iNOS and nNOS) isoforms, is defined. Structures of these novel heterocycles were confirmed based on their...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-10-01
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| Series: | Arabian Journal of Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1878535221003774 |