Mitochondrial fusion but not fission regulates larval growth and synaptic development through steroid hormone production
Mitochondrial fusion and fission affect the distribution and quality control of mitochondria. We show that Marf (Mitochondrial associated regulatory factor), is required for mitochondrial fusion and transport in long axons. Moreover, loss of Marf leads to a severe depletion of mitochondria in neurom...
Main Authors: | Hector Sandoval, Chi-Kuang Yao, Kuchuan Chen, Manish Jaiswal, Taraka Donti, Yong Qi Lin, Vafa Bayat, Bo Xiong, Ke Zhang, Gabriela David, Wu-Lin Charng, Shinya Yamamoto, Lita Duraine, Brett H Graham, Hugo J Bellen |
---|---|
Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2014-10-01
|
Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/03558 |
Similar Items
-
Role of GTPase-Dependent Mitochondrial Dynamins in Heart Diseases
by: Jiangen Liu, et al.
Published: (2021-09-01) -
Mitochondrial fusion/fission dynamics in neurodegeneration and neuronal plasticity
by: A.M. Bertholet, et al.
Published: (2016-06-01) -
The Effect of 4 Weeks of Aerobic Training on Spatial Learning, Memory Performance and Mitochondrial Dynamics in the Hippocampal Tissue of Old Rats
by: Ahmad Fazeli Sani, et al.
Published: (2020-10-01) -
Rapamycin Ameliorates Defects in Mitochondrial Fission and Mitophagy in Glioblastoma Cells
by: Paola Lenzi, et al.
Published: (2021-05-01) -
Mitochondrial Fusion Via OPA1 and MFN1 Supports Liver Tumor Cell Metabolism and Growth
by: Meng Li, et al.
Published: (2020-01-01)