Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis

Transcriptomic analysis across liver diseases reveals disease-modulating activation of constitutive androstane receptor in cholestasis

Background & Aims: Liver diseases are caused by many factors, such as genetics, nutrition, and viruses. Therefore, it is important to delineate transcriptomic changes that occur in various liver diseases. Methods: We performed high-throughput sequencing of mouse livers with diverse types of...

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Bibliographic Details
Main Authors: Bhoomika Mathur, Waqar Arif, Megan E. Patton, Rahiman Faiyaz, Jian Liu, Jennifer Yeh, Sanjiv Harpavat, Kristina Schoonjans, Auinash Kalsotra, Antony M. Wheatley, Sayeepriyadarshini Anakk
Format: Article
Language:English
Published: Elsevier 2020-10-01
Series:JHEP Reports
Subjects:
Bile acids
Cholestasis
Cytochrome p450
Drug metabolism
Liver diseases
Nuclear receptors
Online Access:http://www.sciencedirect.com/science/article/pii/S2589555920300744

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http://www.sciencedirect.com/science/article/pii/S2589555920300744

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