DNA Methylation and Expression Profiles of Whole Blood in Parkinson’s Disease

DNA Methylation and Expression Profiles of Whole Blood in Parkinson’s Disease

Parkinson’s disease (PD) is the second most common age-related neurodegenerative disease. It is presently only accurately diagnosed at an advanced stage by a series of motor deficits, which are predated by a litany of non-motor symptoms manifesting over years or decades. Aberrant epigenetic modifica...

Full description

Bibliographic Details
Main Authors:	Adrienne R. Henderson, Qi Wang, Bessie Meechoovet, Ashley L. Siniard, Marcus Naymik, Matthew De Both, Matthew J. Huentelman, Richard J. Caselli, Erika Driver-Dunckley, Travis Dunckley
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2021-04-01
Series:	Frontiers in Genetics
Subjects:	Parkinson’s DNA methylation RNA-seq biomarker Parkinson’s and related diseases mRNA-seq
Online Access:	https://www.frontiersin.org/articles/10.3389/fgene.2021.640266/full

Similar Items

Evidence for a Pan-Neurodegenerative Disease Response in Huntington's and Parkinson's Disease Expression Profiles
by: Adam Labadorf, et al.
Published: (2018-01-01)

The Effects of Naringenin on miRNA-mRNA Profiles in HepaRG Cells
by: Weiyang Fan, et al.
Published: (2021-02-01)

Deploying new generation sequencing for the study of flesh color depletion in Atlantic Salmon (Salmo salar)
by: Thu Thi Minh Vo, et al.
Published: (2021-07-01)

The Extent of mRNA Editing Is Limited in Chicken Liver and Adipose, but Impacted by Tissular Context, Genotype, Age, and Feeding as Exemplified with a Conserved Edited Site in COG3
by: Pierre-François Roux, et al.
Published: (2016-02-01)

Holo-Seq: single-cell sequencing of holo-transcriptome
by: Zhengyun Xiao, et al.
Published: (2018-10-01)

Identification of mRNAs and lncRNAs Involved in the Regulation of Follicle Development in Goat
by: Zhifeng Zhao, et al.
Published: (2020-12-01)

Corrigendum: Identification of mRNAs and lncRNAs Involved in the Regulation of Follicle Development in Goat
by: Zhifeng Zhao, et al.
Published: (2021-02-01)

Transcriptional Profiles of Long Non-coding RNA and mRNA in Sheep Mammary Gland During Lactation Period
by: Weihao Chen, et al.
Published: (2020-09-01)

Systematic Analysis of Long Non-Coding RNAs and mRNAs in the Ovaries of Duroc Pigs During Different Follicular Stages Using RNA Sequencing
by: Yi Liu, et al.
Published: (2018-06-01)

Integrated mRNA and miRNA profile expression in livers of Jinhua and Landrace pigs
by: Minjie Huang, et al.
Published: (2019-10-01)

Comparative evaluation for the globin gene depletion methods for mRNA sequencing using the whole blood-derived total RNAs
by: Jin Sung Jang, et al.
Published: (2020-12-01)

Whole transcriptome analysis of a reversible neurodegenerative process in <it>Drosophila</it> reveals potential neuroprotective genes
by: Ferreiro María, et al.
Published: (2012-09-01)

Evolutionary Changes in the Interaction of miRNA With mRNA of Candidate Genes for Parkinson’s Disease
by: Saltanat Kamenova, et al.
Published: (2021-03-01)

Long noncoding RNA and mRNA profiling in cetuximab‐resistant colorectal cancer cells by RNA sequencing analysis
by: Changwen Jing, et al.
Published: (2019-04-01)

Genome‑wide integrated analysis demonstrates widespread functions of lncRNAs in mammary gland development and lactation in dairy goats
by: Zhibin Ji, et al.
Published: (2020-03-01)

Analyses of MicroRNA and mRNA Expression Profiles Reveal the Crucial Interaction Networks and Pathways for Regulation of Chicken Breast Muscle Development
by: Yuanfang Li, et al.
Published: (2019-03-01)

The Human Transcriptome: An Unfinished Story
by: Mihaela Pertea
Published: (2012-06-01)

Differential gene expression analysis tools exhibit substandard performance for long non-coding RNA-sequencing data
by: Alemu Takele Assefa, et al.
Published: (2018-07-01)

Identification of genes related to drought in native potatoes using RNA-Seq
by: Roberto Lozano, et al.
Published: (2014-03-01)

Identification of lncRNAs associated with the pathogenesis of ankylosing spondylitis
by: Dan Huang, et al.
Published: (2021-03-01)

OncoLnc: linking TCGA survival data to mRNAs, miRNAs, and lncRNAs
by: Jordan Anaya
Published: (2016-06-01)

Loss of park7 activity has differential effects on expression of iron responsive element (IRE) gene sets in the brain transcriptome in a zebrafish model of Parkinson’s disease
by: Hui Yung Chin, et al.
Published: (2021-05-01)

Hexokinases link DJ-1 to the PINK1/parkin pathway
by: David N. Hauser, et al.
Published: (2017-09-01)

Identification and Characterization of Novel circRNAs Involved in Muscle Growth of Blunt Snout Bream (<i>Megalobrama amblycephala</i>)
by: Lifang Liu, et al.
Published: (2021-09-01)

Analysis of the Gut Microflora in Patients With Parkinson's Disease
by: Miao Jin, et al.
Published: (2019-11-01)

Comprehensive MicroRNA Expression Profile of the Mammary Gland in Lactating Dairy Cows With Extremely Different Milk Protein and Fat Percentages
by: Xiaogang Cui, et al.
Published: (2020-12-01)

Gene expression of Vibrio parahaemolyticus growing in laboratory isolation conditions compared to those common in its natural ocean environment
by: Katherine García, et al.
Published: (2017-05-01)

A genome-wide landscape of mRNAs, lncRNAs, and circRNAs during subcutaneous adipogenesis in pigs
by: Xin Liu, et al.
Published: (2018-11-01)

LncRNA HOXA-AS2 regulates microglial polarization via recruitment of PRC2 and epigenetic modification of PGC-1α expression
by: Xiaodong Yang, et al.
Published: (2021-09-01)

Integrated Analyses Reveal Overexpressed Notch1 Promoting Porcine Satellite Cells’ Proliferation through Regulating the Cell Cycle
by: Yiren Jiao, et al.
Published: (2018-01-01)

Comparison of the RNA Content of Extracellular Vesicles Derived from <i>Paracoccidioides</i> <i>brasiliensis</i> and <i>Paracoccidioides lutzii</i>
by: Roberta Peres da Silva, et al.
Published: (2019-07-01)

Unraveling Targetable Systemic and Cell-Type-Specific Molecular Phenotypes of Alzheimer’s and Parkinson’s Brains With Digital Cytometry
by: Marie C. Bordone, et al.
Published: (2020-12-01)

A comparison between whole transcript and 3’ RNA sequencing methods using Kapa and Lexogen library preparation methods
by: Feiyang Ma, et al.
Published: (2019-01-01)

Comparative analysis of gene expression profiles in differentiated subcutaneous adipocytes between Jiaxing Black and Large White pigs
by: Dawei Zhang, et al.
Published: (2021-01-01)

Genome-Wide Network of lncRNA–mRNA During Ovine Oocyte Development From Germinal Vesicle to Metaphase II in vitro
by: Jun-Jie Wang, et al.
Published: (2020-08-01)

Common microRNA–mRNA Interactions in Different Newcastle Disease Virus-Infected Chicken Embryonic Visceral Tissues
by: Yan-Qing Jia, et al.
Published: (2018-04-01)

Long noncoding RNA and mRNA profiling in MDA-MB-231 cells following RNAi-mediated knockdown of SIRT7
by: Chen KL, et al.
Published: (2017-10-01)

Integrative Analysis of lncRNA-mRNA Profile Reveals Potential Predictors for SAPHO Syndrome
by: Yuxiu Sun, et al.
Published: (2021-06-01)

Expression analysis of genes involved in mitochondrial biogenesis in mice with MPTP-induced model of Parkinson's disease
by: M.M. Rudenok, et al.
Published: (2020-06-01)

Single Eye mRNA-Seq Reveals Normalisation of the Retinal Microglial Transcriptome Following Acute Inflammation
by: Oliver H. Bell, et al.
Published: (2020-01-01)