Genome-wide fitness test and mechanism-of-action studies of inhibitory compounds in Candida albicans.

Candida albicans is a prevalent fungal pathogen amongst the immunocompromised population, causing both superficial and life-threatening infections. Since C. albicans is diploid, classical transmission genetics can not be performed to study specific aspects of its biology and pathogenesis. Here, we e...

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Bibliographic Details
Main Authors: Deming Xu, Bo Jiang, Troy Ketela, Sebastien Lemieux, Karynn Veillette, Nick Martel, John Davison, Susan Sillaots, Steve Trosok, Catherine Bachewich, Howard Bussey, Phil Youngman, Terry Roemer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2007-06-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC1904411?pdf=render