The molecular clock of neutral evolution can be accelerated or slowed by asymmetric spatial structure.

Over time, a population acquires neutral genetic substitutions as a consequence of random drift. A famous result in population genetics asserts that the rate, K, at which these substitutions accumulate in the population coincides with the mutation rate, u, at which they arise in individuals: K = u....

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Bibliographic Details
Main Authors: Benjamin Allen, Christine Sample, Yulia Dementieva, Ruben C Medeiros, Christopher Paoletti, Martin A Nowak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-02-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4342344?pdf=render

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