The molecular clock of neutral evolution can be accelerated or slowed by asymmetric spatial structure.
Over time, a population acquires neutral genetic substitutions as a consequence of random drift. A famous result in population genetics asserts that the rate, K, at which these substitutions accumulate in the population coincides with the mutation rate, u, at which they arise in individuals: K = u....
Main Authors: | Benjamin Allen, Christine Sample, Yulia Dementieva, Ruben C Medeiros, Christopher Paoletti, Martin A Nowak |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2015-02-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4342344?pdf=render |
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