Interferons (<i>IFN-A/-B/-G</i>) Genetic Variants in Patients with Mixed Connective Tissue Disease (MCTD)

Interferons (<i>IFN-A/-B/-G</i>) Genetic Variants in Patients with Mixed Connective Tissue Disease (MCTD)

Mixed connective tissue disease (MCTD) is a rare complex autoimmune disease in which autoantigens are recognized by endosomal TLRs. Their activation induces a higher secretion of the type I interferons, IFN-&#947; and the up-regulation of the INF-inducible genes. The present study aimed to inves...

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Bibliographic Details
Main Authors: Agnieszka Paradowska-Gorycka, Anna Wajda, Barbara Stypinska, Ewa Walczuk, Marcela Walczyk, Anna Felis-Giemza, Aleksandra Poluch, Marzena Olesińska
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Journal of Clinical Medicine
Subjects:
mctd
genetics
ifn
pathogenesis
Online Access:https://www.mdpi.com/2077-0383/8/12/2046

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