Normal SUV values measured from NaF18- PET/CT bone scan studies.

Cancer and metabolic bone diseases can alter the SUV. SUV values have never been measured from healthy skeletons in NaF18-PET/CT bone scans. The primary aim of this study was to measure the SUV values from normal skeletons in NaF18-PET/CT bone scans.A retrospective study was carried out involving Na...

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Main Authors: Aung Zaw Win, Carina Mari Aparici
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4177910?pdf=render
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spelling doaj-2d3d75c345af4a8d80a9a5d8d3ab973b2020-11-25T00:43:58ZengPublic Library of Science (PLoS)PLoS ONE1932-62032014-01-0199e10842910.1371/journal.pone.0108429Normal SUV values measured from NaF18- PET/CT bone scan studies.Aung Zaw WinCarina Mari ApariciCancer and metabolic bone diseases can alter the SUV. SUV values have never been measured from healthy skeletons in NaF18-PET/CT bone scans. The primary aim of this study was to measure the SUV values from normal skeletons in NaF18-PET/CT bone scans.A retrospective study was carried out involving NaF18- PET/CT bone scans that were done at our institution between January 2010 to May 2012. Our excluding criteria was patients with abnormal real function and patients with past history of cancer and metabolic bone diseases including but not limited to osteoporosis, osteopenia and Paget's disease. Eleven studies met all the criteria.The average normal SUVmax values from 11 patients were: cervical vertebrae 6.84 (range 4.38-8.64), thoracic vertebrae 7.36 (range 6.99-7.66), lumbar vertebrae 7.27 (range 7.04-7.72), femoral head 2.22 (range 1.1-4.3), humeral head 1.82 (range 1.2-2.9), mid sternum 5.51 (range 2.6-8.1), parietal bone 1.71 (range 1.3-2.4).According to our study, various skeletal sites have different normal SUV values. SUV values can be different between the normal bones and bones with tumor or metabolic bone disease. SUV can be used to quantify NaF-18 PET/CT studies. If the SUV values of the normal skeleton are known, they can be used in the characterization of bone lesions and in the assessment of treatment response to bone diseases.http://europepmc.org/articles/PMC4177910?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Aung Zaw Win
Carina Mari Aparici
spellingShingle Aung Zaw Win
Carina Mari Aparici
Normal SUV values measured from NaF18- PET/CT bone scan studies.
PLoS ONE
author_facet Aung Zaw Win
Carina Mari Aparici
author_sort Aung Zaw Win
title Normal SUV values measured from NaF18- PET/CT bone scan studies.
title_short Normal SUV values measured from NaF18- PET/CT bone scan studies.
title_full Normal SUV values measured from NaF18- PET/CT bone scan studies.
title_fullStr Normal SUV values measured from NaF18- PET/CT bone scan studies.
title_full_unstemmed Normal SUV values measured from NaF18- PET/CT bone scan studies.
title_sort normal suv values measured from naf18- pet/ct bone scan studies.
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2014-01-01
description Cancer and metabolic bone diseases can alter the SUV. SUV values have never been measured from healthy skeletons in NaF18-PET/CT bone scans. The primary aim of this study was to measure the SUV values from normal skeletons in NaF18-PET/CT bone scans.A retrospective study was carried out involving NaF18- PET/CT bone scans that were done at our institution between January 2010 to May 2012. Our excluding criteria was patients with abnormal real function and patients with past history of cancer and metabolic bone diseases including but not limited to osteoporosis, osteopenia and Paget's disease. Eleven studies met all the criteria.The average normal SUVmax values from 11 patients were: cervical vertebrae 6.84 (range 4.38-8.64), thoracic vertebrae 7.36 (range 6.99-7.66), lumbar vertebrae 7.27 (range 7.04-7.72), femoral head 2.22 (range 1.1-4.3), humeral head 1.82 (range 1.2-2.9), mid sternum 5.51 (range 2.6-8.1), parietal bone 1.71 (range 1.3-2.4).According to our study, various skeletal sites have different normal SUV values. SUV values can be different between the normal bones and bones with tumor or metabolic bone disease. SUV can be used to quantify NaF-18 PET/CT studies. If the SUV values of the normal skeleton are known, they can be used in the characterization of bone lesions and in the assessment of treatment response to bone diseases.
url http://europepmc.org/articles/PMC4177910?pdf=render
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