Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion

Systematic improvements in lentiviral transduction of primary human natural killer cells undergoing ex vivo expansion

Transduction of primary human natural killer (NK) cells with lentiviral vectors has historically been challenging. We sought to evaluate multiple parameters to optimize lentiviral transduction of human peripheral blood NK cells being expanded to large numbers using a good manufacturing practice (GMP...

Full description

Bibliographic Details
Main Authors: David S.J. Allan, Mala Chakraborty, Giacomo C. Waller, Michael J. Hochman, Akkapon Poolcharoen, Robert N. Reger, Richard W. Childs
Format: Article
Language:English
Published: Elsevier 2021-03-01
Series:Molecular Therapy: Methods & Clinical Development
Online Access:http://www.sciencedirect.com/science/article/pii/S2329050121000085

Internet

http://www.sciencedirect.com/science/article/pii/S2329050121000085

Similar Items