Generation of donor organs in chimeric animals via blastocyst complementation

Generation of donor organs in chimeric animals via blastocyst complementation

The lack of organs for transplantation is an important problem in medicine today. The growth of organs in chimeric animals may be the solution of this. The proposed technology is the interspecific blastocyst complementation method in combination with genomic editing for obtaining “free niches” and p...

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Bibliographic Details
Main Authors: T. I. Babochkina, L. A. Gerlinskaya, M. P. Moshkin
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2020-12-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
chimerism
interspecies chimera
embryo sc
ipsc
crispr/cas9
organ generation
Online Access:https://vavilov.elpub.ru/jour/article/view/2852

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