Non-Homologous End Joining Plays a Key Role in Transgene Concatemer Formation in Transgenic Zebrafish Embryos

<p>This study focused on concatemer formation and integration pattern of transgenes in zebrafish embryos. A reporter plasmid based on enhanced green fluorescent protein (eGFP) driven by Cytomegalovirus (CMV) promoter, pCMV-pax6in-eGFP, was constructed to reflect transgene behavior in the host...

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Bibliographic Details
Main Author: Jun Dai, Xiaojuan Cui, Zuoyan Zhu, Wei Hu
Format: Article
Language:English
Published: Ivyspring International Publisher 2010-01-01
Series:International Journal of Biological Sciences
Online Access:http://www.biolsci.org/v06p0756.htm