Amlodipine and Atorvastatin Improved Hypertensive Cardiac Remodeling through Regulation of MMPs/TIMPs in SHR Rats

Amlodipine and Atorvastatin Improved Hypertensive Cardiac Remodeling through Regulation of MMPs/TIMPs in SHR Rats

Background: MMPs/TIMPs system is well known to play important roles in pressure overload-induced cardiac remodeling, and Amlodipine and Atorvastatin have been showed to exert favourable protective effects on cardiovascular disease, however, it is not clear whether Amlodipine and Atorvastatin can imp...

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Bibliographic Details
Main Authors:	Jingchao Lu, Jie Hao, Hong Du, Bing Xiao, Yue Li, Xiuchun Yang, Wei Cui
Format:	Article
Language:	English
Published:	Cell Physiol Biochem Press GmbH & Co KG 2016-06-01
Series:	Cellular Physiology and Biochemistry
Subjects:	Matrix metalloproteinases Tissue inhibitors of matrix metalloproteinases Amlodipine Atorvastatin Cardiac hypertrophy Spontaneous hypertension
Online Access:	http://www.karger.com/Article/FullText/445604

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