Heterologous Expression of the Pathogen-Specific LIC11711 Gene in the Saprophyte <i>L. biflexa</i> Increases Bacterial Binding to Laminin and Plasminogen

Heterologous Expression of the Pathogen-Specific LIC11711 Gene in the Saprophyte <i>L. biflexa</i> Increases Bacterial Binding to Laminin and Plasminogen

Leptospirosis is a febrile disease and the etiological agents are pathogenic bacteria of the genus <i>Leptospira</i>. The leptospiral virulence mechanisms are not fully understood and the application of genetic tools is still limited, despite advances in molecular biology techniques. The...

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Bibliographic Details
Main Authors: Leandro Toshio Kochi, Luis Guilherme Virgílio Fernandes, Ana Lucia Tabet Oller Nascimento
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Pathogens
Subjects:
<i>Leptospira</i>
leptospirosis
virulence
Online Access:https://www.mdpi.com/2076-0817/9/8/599

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