Human CD8 T cells generated <it>in vitro </it>from hematopoietic stem cells are functionally mature

<p>Abstract</p> <p>Background</p> <p>T cell development occurs within the highly specialized thymus. Cytotoxic CD8 T cells are critical in adaptive immunity by targeting virally infected or tumor cells. In this study, we addressed whether functional CD8 T cells can be g...

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Bibliographic Details
Main Authors: Zúñiga-Pflücker Juan, La Motte-Mohs Ross N, Herer Elaine, Awong Génève
Format: Article
Language:English
Published: BMC 2011-03-01
Series:BMC Immunology
Online Access:http://www.biomedcentral.com/1471-2172/12/22