Appropriate Sequence for Afatinib and Cisplatin Combination Improves Anticancer Activity in Head and Neck Squamous Cell Carcinoma

Appropriate Sequence for Afatinib and Cisplatin Combination Improves Anticancer Activity in Head and Neck Squamous Cell Carcinoma

Despite a better understanding in head and neck tumors pathogenesis as well as improvements in radiotherapy and surgery, locally advanced head and neck squamous cell carcinoma (HNSCC) remains of poor prognosis. One promising target is the epidermal growth factor receptor (EGFR), which is overexpress...

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Bibliographic Details
Main Authors: Eleonore Longton, Kathleen Schmit, Maude Fransolet, François Clement, Carine Michiels
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Oncology
Subjects:
head and neck squamous cell carcinoma
afatinib
combined therapy
treatment schedule
cisplatin
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00432/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2018.00432/full

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