Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity
Phytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 1–3 and five known analogues 4–8. Structural elucidations of 1–3 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ROESY) NMR spectroscopy, in addition to high reso...
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| Format: | Article |
| Language: | English |
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MDPI AG
2013-08-01
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| Series: | Molecules |
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| Online Access: | http://www.mdpi.com/1420-3049/18/8/9663 |
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doaj-2d1027e7f8fb49b6827e923a8899c68f2020-11-24T22:00:07ZengMDPI AGMolecules1420-30492013-08-011889663966910.3390/molecules18089663Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV ActivityQiu-Fen HuXue-Mei GaoXiu-Ping LuYu-Ping WuWei ZhaoGuang-Hui KongZhen-Yuan XiaPhytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 1–3 and five known analogues 4–8. Structural elucidations of 1–3 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ROESY) NMR spectroscopy, in addition to high resolution mass spectrometry. Compounds 1–3 showed anti-TMV activities, with inhibition rates above 20%, especially for 1, which had a lower IC50 value of 21.4 µM.http://www.mdpi.com/1420-3049/18/8/9663Garcinia paucinervisxanthonesanti-tobacco mosaic virus |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
Qiu-Fen Hu Xue-Mei Gao Xiu-Ping Lu Yu-Ping Wu Wei Zhao Guang-Hui Kong Zhen-Yuan Xia |
| spellingShingle |
Qiu-Fen Hu Xue-Mei Gao Xiu-Ping Lu Yu-Ping Wu Wei Zhao Guang-Hui Kong Zhen-Yuan Xia Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity Molecules Garcinia paucinervis xanthones anti-tobacco mosaic virus |
| author_facet |
Qiu-Fen Hu Xue-Mei Gao Xiu-Ping Lu Yu-Ping Wu Wei Zhao Guang-Hui Kong Zhen-Yuan Xia |
| author_sort |
Qiu-Fen Hu |
| title |
Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity |
| title_short |
Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity |
| title_full |
Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity |
| title_fullStr |
Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity |
| title_full_unstemmed |
Three Novel Xanthones from Garcinia paucinervis and Their Anti-TMV Activity |
| title_sort |
three novel xanthones from garcinia paucinervis and their anti-tmv activity |
| publisher |
MDPI AG |
| series |
Molecules |
| issn |
1420-3049 |
| publishDate |
2013-08-01 |
| description |
Phytochemical investigations of the leaves of Garcinia paucinervis resulted in the isolation of three new xanthones 1–3 and five known analogues 4–8. Structural elucidations of 1–3 were performed by spectral methods such as 1D and 2D (HMQC, HMBC, and ROESY) NMR spectroscopy, in addition to high resolution mass spectrometry. Compounds 1–3 showed anti-TMV activities, with inhibition rates above 20%, especially for 1, which had a lower IC50 value of 21.4 µM. |
| topic |
Garcinia paucinervis xanthones anti-tobacco mosaic virus |
| url |
http://www.mdpi.com/1420-3049/18/8/9663 |
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