H2B Type 1-K Accumulates in Senescent Fibroblasts with Persistent DNA Damage along with Methylated and Phosphorylated Forms of HMGA1

Cellular senescence is a state of terminal proliferative arrest that plays key roles in aging by preventing stem cell renewal and by inducing the expression of a series of inflammatory factors including many secreted proteins with paracrine effects. The in vivo identification of senescent cells is d...

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Bibliographic Details
Main Authors: Kévin Contrepois, Carl Mann, François Fenaille
Format: Article
Language:English
Published: MDPI AG 2021-06-01
Series:Proteomes
Subjects:
Online Access:https://www.mdpi.com/2227-7382/9/2/30