Global analysis of primary mesenchyme cell cis-regulatory modules by chromatin accessibility profiling

Global analysis of primary mesenchyme cell cis-regulatory modules by chromatin accessibility profiling

Abstract Background The developmental gene regulatory network (GRN) that underlies skeletogenesis in sea urchins and other echinoderms is a paradigm of GRN structure, function, and evolution. This transcriptional network is deployed selectively in skeleton-forming primary mesenchyme cells (PMCs) of...

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Bibliographic Details
Main Authors: Tanvi Shashikant, Jian Ming Khor, Charles A. Ettensohn
Format: Article
Language:English
Published: BMC 2018-03-01
Series:BMC Genomics
Subjects:
Primary mesenchyme cells
Sea urchins
Skeletogenesis
Gene regulatory network
DNase-seq
ATAC-seq
Online Access:http://link.springer.com/article/10.1186/s12864-018-4542-z

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