Morphological features of immune inflammation in patients with persistent post-traumatic uveitis
Purpose: to study the morphology of immune inflammation in patients with long-term posttraumatic uveitis. Material and methods. 54 patients who had one of their eyes removed after trauma and/or the results of surgical intervention were examined, followed by morphological examination of the removed e...
| Main Authors: | , , |
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| Format: | Article |
| Language: | Russian |
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Real Time Ltd
2020-05-01
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| Series: | Российский офтальмологический журнал |
| Subjects: | |
| Online Access: | https://roj.igb.ru/jour/article/view/421 |
| Summary: | Purpose: to study the morphology of immune inflammation in patients with long-term posttraumatic uveitis. Material and methods. 54 patients who had one of their eyes removed after trauma and/or the results of surgical intervention were examined, followed by morphological examination of the removed eyes. The eyes were divided into three groups based on the type of trauma. Group I consisted of 20 eyes removed in the outcome of contusion injury. Group II was formed from 16 eyes removed as the outcome of a penetrating wound. Group III included 18 removed eyes after penetrating surgical interventions performed for retinal detachment and/or antiglaucomatous operations. Results. Morphological signs of immune inflammation were found in at least half of the cases in each of the studied groups. In group I (patients with concussion injury outcome) the incidence was the highest and amounted to 65 %, whilst in group II and III the signs were revealed in 56.3 %, and 50 %, respectively. In group III, all cases with immune post-traumatic inflammation referred to patients who underwent vitreoretinal interventions with the introduction of silicone oil into the vitreal cavity. Conclusions. According to comprehensive clinical and morphological study of 54 enucleated eyes, morphopathogenesis of immune inflammation with characteristic lymphoid infiltration and formation of lymphoid nodules was revealed in 57.4 % of cases. In patients with morphologically detected immune uveitis in history, exacerbation of post-traumatic inflammatory process was found to be related to acute respiratory viral diseases in 45.1 % of cases, which cannot exclude a possible role of the infectious factor in the development of an inflammatory reaction with signs of immune-based uveitis. |
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| ISSN: | 2072-0076 2587-5760 |