eQTL epistasis – challenges and computational approaches

eQTL epistasis – challenges and computational approaches

The determination of eQTL epistasis - a form of functional interaction between genetic loci that affect gene expression - is an important step towards the thorough understanding of gene regulation. Since gene expression has emerged as an intermediate molecular phenotype eQTL epistasis might help to...

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Bibliographic Details
Main Authors: Yang eHuang, Stefan eWuchty, Teresa M Przytycka
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-05-01
Series:Frontiers in Genetics
Subjects:
eQTL
Genetic association
Epostasis
Genetic crosses
network modules
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00051/full

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