Building de novo cryo-electron microscopy structures collaboratively with citizen scientists.

With the rapid improvement of cryo-electron microscopy (cryo-EM) resolution, new computational tools are needed to assist and improve upon atomic model building and refinement options. This communication demonstrates that microscopists can now collaborate with the players of the computer game Foldit...

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Bibliographic Details
Main Authors: Firas Khatib, Ambroise Desfosses, Foldit Players, Brian Koepnick, Jeff Flatten, Zoran Popović, David Baker, Seth Cooper, Irina Gutsche, Scott Horowitz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-11-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000472