Cooperative Cellular Uptake and Activity of Octaarginine Antisense Peptide Nucleic Acid (PNA) Conjugates

Cooperative Cellular Uptake and Activity of Octaarginine Antisense Peptide Nucleic Acid (PNA) Conjugates

Cellular uptake and antisense activity of <span style="font-variant: small-caps;">d</span>-octaarginine conjugated peptide nucleic acids (PNAs) is shown to exhibit pronounced cooperativity in serum-containing medium, in particular by being enhanced by analogous mis-match PNA&am...

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Bibliographic Details
Main Authors: Mahdi Ghavami, Takehiko Shiraishi, Peter E. Nielsen
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Biomolecules
Subjects:
antisense
pna delivery
octaarginine conjugate
cell-penetrating peptides
self-assembled nanoparticles
Online Access:https://www.mdpi.com/2218-273X/9/10/554

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