CircHIPK3 Promotes Pyroptosis in Acinar Cells Through Regulation of the miR-193a-5p/GSDMD Axis

CircHIPK3 Promotes Pyroptosis in Acinar Cells Through Regulation of the miR-193a-5p/GSDMD Axis

Acute pancreatitis (AP), especially severe acute pancreatitis (SAP), is an extremely dangerous illness with a high mortality rate. Pyroptotic cells release their cellular contents and inflammatory factors, aggravating the inflammatory response. Pyroptosis may be the main mode of acinar cell death du...

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Bibliographic Details
Main Authors: Jiale Wang, Xia Li, Yunfei Liu, Cheng Peng, Hongwei Zhu, Guangping Tu, Xiao Yu, Zhiqiang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-04-01
Series:Frontiers in Medicine
Subjects:
acute pancreatitis
circular RNA
pyroptosis
microRNA
gasdermin family
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00088/full

Internet

https://www.frontiersin.org/article/10.3389/fmed.2020.00088/full

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