Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model

Tissue engineering approaches using progenitor cells such as mesenchymal stromal cells (MSCs) represent a promising strategy to regenerate bone. Previous work has demonstrated the potential of chondrogenically primed human MSCs to recapitulate the process of endochondral ossification and form mature...

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Main Authors: Niamh Fahy, Virginia Palomares Cabeza, Andrea Lolli, Janneke Witte-Bouma, Ana Merino, Yanto Ridwan, Eppo B. Wolvius, Martin J. Hoogduijn, Eric Farrell, Pieter A. J. Brama
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
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Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.715267/full

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