Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model

Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model

Tissue engineering approaches using progenitor cells such as mesenchymal stromal cells (MSCs) represent a promising strategy to regenerate bone. Previous work has demonstrated the potential of chondrogenically primed human MSCs to recapitulate the process of endochondral ossification and form mature...

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Bibliographic Details
Main Authors: Niamh Fahy, Virginia Palomares Cabeza, Andrea Lolli, Janneke Witte-Bouma, Ana Merino, Yanto Ridwan, Eppo B. Wolvius, Martin J. Hoogduijn, Eric Farrell, Pieter A. J. Brama
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-09-01
Series:Frontiers in Immunology
Subjects:
mesenchymal stem cells
endochondral ossification
xenogeneic
immunocompetence
adaptive immunity
innate immunity
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.715267/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.715267/full

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