Investigating the Release of Methotrexate and 5-Fluorouracil Anticancer Drugs from Multi-Layered Nanofiber Structure of Polycaprolactone/Chitosan

Investigating the Release of Methotrexate and 5-Fluorouracil Anticancer Drugs from Multi-Layered Nanofiber Structure of Polycaprolactone/Chitosan

In this study, seven-layer nanofiber structures consisting of polycaprolactone/ chitosan polymers loaded with methotrexate and 5-fluorouracil anti-cancer drugs, for controlled drug delivery, were produced and evaluated. For this purpose, the second, fourth and sixth layers were loaded with drug and...

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Bibliographic Details
Main Authors: N. Poursharifi, D. Semnani, P. Soltani, S. Amanpour
Format: Article
Language:fas
Published: Isfahan University of Technology 2020-01-01
Series:Journal of Advanced Materials in Engineering
Subjects:
drug delivery
nanofibers
polycaprolactone
chitosan
5-fluorouracil
methotrexate.
Online Access:http://jame.iut.ac.ir/article-1-1035-en.html

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