CD4+ FOXP3+ Regulatory T Cells Exhibit Impaired Ability to Suppress Effector T Cell Proliferation in Patients with Turner Syndrome.

CD4+ FOXP3+ Regulatory T Cells Exhibit Impaired Ability to Suppress Effector T Cell Proliferation in Patients with Turner Syndrome.

We investigated whether the frequency, phenotype, and suppressive function of CD4+ FOXP3+ regulatory T cells (Tregs) are altered in young TS patients with the 45,X karyotype compared to age-matched controls.Peripheral blood mononuclear cells from young TS patients (n = 24, 17.4-35.9 years) and healt...

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Bibliographic Details
Main Authors: Young Ah Lee, Hang-Rae Kim, Jeong Seon Lee, Hae Woon Jung, Hwa Young Kim, Gyung Min Lee, Jieun Lee, Ji Hyun Sim, Sae Jin Oh, Doo Hyun Chung, Choong Ho Shin, Sei Won Yang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4692523?pdf=render

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http://europepmc.org/articles/PMC4692523?pdf=render

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