Palmitic Acid Methyl Ester and Its Relation to Control of Tone of Human Visceral Arteries and Rat Aortas by Perivascular Adipose Tissue

Palmitic Acid Methyl Ester and Its Relation to Control of Tone of Human Visceral Arteries and Rat Aortas by Perivascular Adipose Tissue

Background: Perivascular adipose tissue (PVAT) exerts anti-contractile effects on visceral arteries by release of various perivascular relaxing factors (PVRFs) and opening voltage-gated K+ (Kv) channels in vascular smooth muscle cells (VSMCs). Palmitic acid methyl ester (PAME) has been proposed as t...

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Bibliographic Details
Main Authors: Ning Wang, Artur Kuczmanski, Galyna Dubrovska, Maik Gollasch
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-05-01
Series:Frontiers in Physiology
Subjects:
XE991
adipocyte-derived relaxing factor (ADRF)
perivascular adipose tissue (PVAT)
KCNQ channels
Kv channels
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2018.00583/full

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