The Ratio of Factor VIIa:Tissue Factor Content within Microvesicles Determines the Differential Influence on Endothelial Cells

The Ratio of Factor VIIa:Tissue Factor Content within Microvesicles Determines the Differential Influence on Endothelial Cells

Tissue factor (TF)-positive microvesicles from various sources can promote cellular proliferation or alternatively induce apoptosis, but the determining factors are unknown. In this study the hypothesis that the ratio of fVIIa:TF within microvesicles determines this outcome was examined. Microvesicl...

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Bibliographic Details
Main Authors: Yahya Madkhali, Sophie Featherby, Mary E. Collier, Anthony Maraveyas, John Greenman, Camille Ettelaie
Format: Article
Language:English
Published: Georg Thieme Verlag KG 2019-04-01
Series:TH Open
Subjects:
tissue factor
microvesicles
protease-activated receptor-2
apoptosis
cell proliferation
factor viia
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1688934

Internet

http://www.thieme-connect.de/DOI/DOI?10.1055/s-0039-1688934

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