Local recurrence as a first sign of parathyroid malignancy! Need to redefine the criteria for diagnosis of parathyroid carcinoma

• Main Authors: P V Pradeep, Vydehi Venkata Bheemaraju
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2013-01-01
• Series: Indian Journal of Endocrinology and Metabolism
• Subjects: Adenoma; parathyroid carcinoma; primary hyperparathyroidism
• Online Access: http://www.ijem.in/article.asp?issn=2230-8210;year=2013;volume=17;issue=5;spage=927;epage=929;aulast=Pradeep

Pathological criteria alone do not make an accurate diagnosis of parathyroid carcinoma in cases of well-defined organ contained lesion without local and distant metastasis. Intra-operative appearance of pale, grayish, firm tumor is highly suggestive of parathyroid carcinoma, even though this finding is not included in the pathological criteria for diagnosing a malignancy. Gross features of the tumor also should be added to the pathological criteria so as to ensure an accurate assessment of the biological behavior of the parathyroid tumor.