The role of glucocorticoid receptor phosphorylation in Mcl-1 and NOXA gene expression

<p>Abstract</p> <p>Background</p> <p>The cyclin-dependent kinase (CDK) and mitogen-activated protein kinase (MAPK) mediated phosphorylation of glucocorticoid receptor (GR) exerts opposite effects on GR transcriptional activity and affects other posttranslational modific...

Full description

Bibliographic Details
Main Authors: Demonacos Constantinos, Berrou Ilhem, Xenaki Georgia, Rajendran Ramkumar, Lynch James T, Krstic-Demonacos Marija
Format: Article
Language:English
Published: BMC 2010-02-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/9/1/38