Bone is not essential for osteoclast activation.

Bone is not essential for osteoclast activation.

The mechanism whereby bone activates resorptive behavior in osteoclasts, the cells that resorb bone, is unknown. It is known that α(v)β(3) ligands are important, because blockade of α(v)β(3) receptor signaling inhibits bone resorption, but this might be through inhibition of adhesion or migration ra...

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Bibliographic Details
Main Authors:	Karen Fuller, Jade L Ross, Kinga A Szewczyk, Raymond Moss, Tim J Chambers
Format:	Article
Language:	English
Published:	Public Library of Science (PLoS) 2010-09-01
Series:	PLoS ONE
Online Access:	http://europepmc.org/articles/PMC2941467?pdf=render

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