Inhibition of HDAC6 Attenuates Tumor Growth of Non-Small Cell Lung Cancer

Inhibition of HDAC6 Attenuates Tumor Growth of Non-Small Cell Lung Cancer

Histone deacetylase 6 (HDAC6) regulates cytoplasmic signaling networks through deacetylation of various cytoplasmic substrates and serves as a key member of the ubiquitin proteasome system (UPS). This study is focused on HDAC6 regulation of the Notch1 receptor that plays a crucial role in tumor grow...

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Bibliographic Details
Main Authors:	Brian Deskin, Qinyan Yin, Yan Zhuang, Shigeki Saito, Bin Shan, Joseph A. Lasky
Format:	Article
Language:	English
Published:	Elsevier 2020-02-01
Series:	Translational Oncology
Online Access:	http://www.sciencedirect.com/science/article/pii/S1936523319306163

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