Add-on effect of probucol in atherosclerotic, cholesterol-fed rabbits treated with atorvastatin.

OBJECTIVE: Lowering the blood concentration of low-density lipoprotein (LDL) cholesterol is the primary strategy employed in treating atherosclerotic disorders; however, most commonly prescribed statins prevent cardiovascular events in just 30% to 40% of treated patients. Therefore, additional treat...

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Bibliographic Details
Main Authors: Yuka Keyamura, Chifumi Nagano, Masayuki Kohashi, Manabu Niimi, Masanori Nozako, Takashi Koyama, Reiko Yasufuku, Ayako Imaizumi, Hiroyuki Itabe, Tomohiro Yoshikawa
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4014602?pdf=render