Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis

Cell Cycle Deregulation in Ewing's Sarcoma Pathogenesis

Ewing's sarcoma is a highly aggressive pediatric tumor of bone that usually contains the characteristic chromosomal translocation t(11;22)(q24;q12). This translocation encodes the oncogenic fusion protein EWS/FLI, which acts as an aberrant transcription factor to deregulate target genes necessa...

Full description

Bibliographic Details
Main Authors:	Ashley A. Kowalewski, R. Lor Randall, Stephen L. Lessnick
Format:	Article
Language:	English
Published:	Hindawi Limited 2011-01-01
Series:	Sarcoma
Online Access:	http://dx.doi.org/10.1155/2011/598704

Similar Items

Microsatellites with Macro-Influence in Ewing Sarcoma
by: Stephen L. Lessnick, et al.
Published: (2012-07-01)

EWS/FLI mediates transcriptional repression via NKX2.2 during oncogenic transformation in Ewing's sarcoma.
by: Leah A Owen, et al.
Published: (2008-04-01)

Increased risk for other cancers in individuals with Ewing sarcoma and their relatives
by: Diana Abbott, et al.
Published: (2019-12-01)

Is There a Predisposition Gene for Ewing's Sarcoma?
by: R. L. Randall, et al.
Published: (2010-01-01)

Salient Features of Mesenchymal Stem Cells – Implications for Ewing Sarcoma Modeling
by: Michael James Monument, et al.
Published: (2013-02-01)

Recent advances in targeted therapy for Ewing sarcoma [version 1; referees: 2 approved]
by: Kathleen I. Pishas, et al.
Published: (2016-08-01)

BCL11B is up-regulated by EWS/FLI and contributes to the transformed phenotype in Ewing sarcoma.
by: Elizabeth T Wiles, et al.
Published: (2013-01-01)

Identification of two types of GGAA-microsatellites and their roles in EWS/FLI binding and gene regulation in Ewing sarcoma.
by: Kirsten M Johnson, et al.
Published: (2017-01-01)

The Controversial Role of Autophagy in Ewing Sarcoma Pathogenesis—Current Treatment Options
by: Evangelos Koustas, et al.
Published: (2021-02-01)

Ewing`s Sarcoma
by: Agnieszka Budny, et al.
Published: (2017-06-01)

Ewing Sarcoma
by: Hee Young Ju
Published: (2019-04-01)

Network potential identifies therapeutic miRNA cocktails in Ewing sarcoma
by: Dhawan, A., et al.
Published: (2021)

Cutaneous Ewing Sarcoma and Ewing Sarcoma of the Bone: Distinct Diseases
by: Montreh Tavakkoli, et al.
Published: (2018-11-01)

Potential for Modulation of the Fas Apoptotic Pathway by Epidermal Growth Factor in Sarcomas
by: David E. Joyner, et al.
Published: (2011-01-01)

Identifying States of Collateral Sensitivity during the Evolution of Therapeutic Resistance in Ewing's Sarcoma
by: Jessica A. Scarborough, et al.
Published: (2020-07-01)

Targeting glutathione S-transferase M4 in Ewing sarcoma
by: Rupeng eZhuo, et al.
Published: (2014-08-01)

Role of Radiation Therapy in Adult Extraskeletal Ewing’s Sarcoma Patients Treated with Chemotherapy and Surgery
by: Augustine M. Saiz, et al.
Published: (2019-01-01)

NK cell recognition of Ewing's sarcoma
by: Holmes, Tim Dunstan
Published: (2008)

Ewing’s sarcoma of the mobile spine
by: A. Khelifa, et al.
Published: (2019-09-01)

Sarcoma de Ewing
by: Erick Héctor Hernández González, et al.
Published: (2013-01-01)

Fenretinide-induced cell death in Ewing's sarcoma family of tumours
by: Myatt, Stephen Samuel
Published: (2006)

Sarcoma de Ewing en paciente masculino Ewing's sarcoma in a male patient
by: Eddy Millán Escalona, et al.
Published: (2010-09-01)

Survey of Paediatric Oncologists and Pathologists regarding Their Views and Experiences with Variant Translocations in Ewing and Ewing-Like Sarcoma: A Report of the Children’s Oncology Group
by: Michael D. Kinnaman, et al.
Published: (2020-01-01)

Mesenchymal Stem Cells and the Origin of Ewing's Sarcoma
by: Patrick P. Lin, et al.
Published: (2011-01-01)

Epigenetic regulation of Ewing's sarcoma stem cells
by: Albadrani, Ghadeer Mohsen
Published: (2017)

Signature-based small molecule screening identifies cytosine arabinoside as an EWS/FLI modulator in Ewing sarcoma.
by: Kimberly Stegmaier, et al.
Published: (2007-04-01)

Ewing’s Sarcoma Presenting as Pleural Effusion
by: Nuzhat Husain, et al.
Published: (2011-09-01)

Targeted Therapy of Ewing's Sarcoma
by: Vivek Subbiah, et al.
Published: (2011-01-01)

Ewing's Sarcoma and Second Malignancies
by: Joshua D. Schiffman, et al.
Published: (2011-01-01)

Role of immunotherapy in Ewing sarcoma
by: Erin Morales, et al.
Published: (2020-07-01)

Primary Ewings Sarcoma of the Lung
by: Kunal K Deokar, et al.
Published: (2015-01-01)

The many faces of Ewing sarcoma
by: Asharf Fouda, et al.
Published: (2009-07-01)

Cavernous Sinus Ewing's Sarcoma
by: André Simis, et al.

Ewing's sarcoma of the head and neck
by: Adriano Santana Fonseca, et al.
Published: (2000-11-01)

MicroRNAs in Ewing Sarcoma
by: Layne eDylla, et al.
Published: (2013-03-01)

Rhabdomyosarcoma and Extraosseous Ewing Sarcoma
by: Juan P. Gurria, et al.
Published: (2018-12-01)

Ewing’s Sarcoma of the Cranial Vault
by: Geetha Narayanan, et al.
Published: (2016-12-01)

Ewing's sarcoma of retroperitoneal presentation
by: Carlos Pérez Díaz
Published: (2018-06-01)

The Molecular Basis of Sarcoma
by: Stephen L. Lessnick, et al.
Published: (2011-01-01)

Ewing’s sarcoma of the rib in a child
by: S Van Petegem, et al.
Published: (2012-11-01)

Cannot write session to /tmp/vufind_sessions/sess_atqlvhrvmqtl3048vc6ed93eb5