Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents

In this review we summarize the most important procedures for the preparation of functionalized organzinc and organomagnesium reagents. In addition, new methods for the preparation of polyfunctional aryl- and heteroaryl zinc- and magnesium compounds, as well as new Pd-catalyzed cross-coupling reacti...

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Main Authors: Paul Knochel, Matthias A. Schade, Sebastian Bernhardt, Georg Manolikakes, Albrecht Metzger, Fabian M. Piller, Christoph J. Rohbogner, Marc Mosrin
Format: Article
Language:English
Published: Beilstein-Institut 2011-09-01
Series:Beilstein Journal of Organic Chemistry
Subjects:
Online Access:https://doi.org/10.3762/bjoc.7.147
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spelling doaj-2c5fa8f8138e450e8cee7899a5a7d5e02021-02-02T08:46:30ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972011-09-01711261127710.3762/bjoc.7.1471860-5397-7-147Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagentsPaul Knochel0Matthias A. Schade1Sebastian Bernhardt2Georg Manolikakes3Albrecht Metzger4Fabian M. Piller5Christoph J. Rohbogner6Marc Mosrin7Department Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyDepartment Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyDepartment Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyDepartment Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyDepartment Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyDepartment Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyDepartment Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyDepartment Chemie, Ludwig-Maximilians-Universität München, Butenandtstr. 5-13, 81377 München, GermanyIn this review we summarize the most important procedures for the preparation of functionalized organzinc and organomagnesium reagents. In addition, new methods for the preparation of polyfunctional aryl- and heteroaryl zinc- and magnesium compounds, as well as new Pd-catalyzed cross-coupling reactions, are reported herein. Experimental details are given for the most important reactions in the of this article.https://doi.org/10.3762/bjoc.7.147cross-couplingheterocyclesinsertionmetalationorganomagnesiumorganozinc
collection DOAJ
language English
format Article
sources DOAJ
author Paul Knochel
Matthias A. Schade
Sebastian Bernhardt
Georg Manolikakes
Albrecht Metzger
Fabian M. Piller
Christoph J. Rohbogner
Marc Mosrin
spellingShingle Paul Knochel
Matthias A. Schade
Sebastian Bernhardt
Georg Manolikakes
Albrecht Metzger
Fabian M. Piller
Christoph J. Rohbogner
Marc Mosrin
Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
Beilstein Journal of Organic Chemistry
cross-coupling
heterocycles
insertion
metalation
organomagnesium
organozinc
author_facet Paul Knochel
Matthias A. Schade
Sebastian Bernhardt
Georg Manolikakes
Albrecht Metzger
Fabian M. Piller
Christoph J. Rohbogner
Marc Mosrin
author_sort Paul Knochel
title Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
title_short Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
title_full Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
title_fullStr Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
title_full_unstemmed Functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
title_sort functionalization of heterocyclic compounds using polyfunctional magnesium and zinc reagents
publisher Beilstein-Institut
series Beilstein Journal of Organic Chemistry
issn 1860-5397
publishDate 2011-09-01
description In this review we summarize the most important procedures for the preparation of functionalized organzinc and organomagnesium reagents. In addition, new methods for the preparation of polyfunctional aryl- and heteroaryl zinc- and magnesium compounds, as well as new Pd-catalyzed cross-coupling reactions, are reported herein. Experimental details are given for the most important reactions in the of this article.
topic cross-coupling
heterocycles
insertion
metalation
organomagnesium
organozinc
url https://doi.org/10.3762/bjoc.7.147
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