High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner

High-fat diet alters stress behavior, inflammatory parameters and gut microbiota in Tg APP mice in a sex-specific manner

Long-term high-fat diet (HFD) consumption commonly leads to obesity, a major health concern of western societies and a risk factor for Alzheimer's disease (AD). Both conditions present glial activation and inflammation and show sex differences in their incidence, clinical manifestation, and dis...

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Bibliographic Details
Main Authors: Natalia Yanguas-Casás, Cristina Torres, Andrea Crespo-Castrillo, Sonia Diaz-Pacheco, Kiera Healy, Catherine Stanton, Julie A. Chowen, Luis M. Garcia-Segura, Maria Angeles Arevalo, John F. Cryan, Maria L. de Ceballos
Format: Article
Language:English
Published: Elsevier 2021-11-01
Series:Neurobiology of Disease
Subjects:
Anxiety
Alzheimer's disease
Cytokines
Diet
Inflammation
Microbiota
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996121002448

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