SUPPRESSION OF MICE IMMUNE RESPONSE BY ANTIMACROPHAGE SERUM TREATEMENT AND ITS RECONSTITUATION BY MACROPHAGE TRANSPLANTATION

SUPPRESSION OF MICE IMMUNE RESPONSE BY ANTIMACROPHAGE SERUM TREATEMENT AND ITS RECONSTITUATION BY MACROPHAGE TRANSPLANTATION

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The immunosuppressive effect of antimacrophage serum (AMS) on the primary immune response of mice to sheep red blood cells (SRBC) was studied. AMS, given before a small dose of antigen, abrogated the immune response. Transplantation of normal, galss-adherent macrophages enabled AMS-treated animals t...

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Bibliographic Details
Main Authors: N. Mohagheghpour, LK. Nafici
Format: Article
Language:English
Published: Tehran University of Medical Sciences 1975-08-01
Series:Iranian Journal of Public Health
Subjects:
Immunosuppressive effect
Antimacrophage serum
Transplantation
Online Access:http://journals.tums.ac.ir/PdfMed.aspx?pdf_med=/upload_files/pdf/10723.pdf&manuscript_id=10723
Description
Summary:The immunosuppressive effect of antimacrophage serum (AMS) on the primary immune response of mice to sheep red blood cells (SRBC) was studied. AMS, given before a small dose of antigen, abrogated the immune response. Transplantation of normal, galss-adherent macrophages enabled AMS-treated animals to respond to SRBC, while administration of lymph node lymphocytes did not reveres AMS - induced immunosuppression significantly.
ISSN:2251-6085

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