BAC-FISH assays delineate complex chromosomal rearrangements in a case of post-Chernobyl childhood thyroid cancer.

BAC-FISH assays delineate complex chromosomal rearrangements in a case of post-Chernobyl childhood thyroid cancer.

Structural chromosome aberrations are known hallmarks of many solid tumors. In the papillary form of thyroid cancer (PTC), for example, activation of the receptor tyrosine kinase (RTK) genes, RET and neurotrophic tyrosine kinase receptor type I (NTRK1) by intra- and interchromosomal rearrangements h...

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Bibliographic Details
Main Authors: Horst F Zitzelsberger, Jingly F Weier, Mei Wang, Chun-Mei Lu, Adolf Baumgartner, Johnson Kwan, Heinz-Ulrich G Weier
Format: Article
Language:English
Published: Via Medica 2009-12-01
Series:Folia Histochemica et Cytobiologica
Online Access:http://czasopisma.viamedica.pl/fhc/article/view/4345

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