Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system

Genome-wide association study for biomarker identification of Rapamycin and Everolimus using a lymphoblastoid cell line system

The mammalian target of rapamycin (mTOR) inhibitors, a set of promising potential anti-cancer agents, has shown response variability among individuals. This study aimed to identify novel biomarkers and mechanisms that might influence the response to Rapamycin and Everolimus. Genome-wide associatio...

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Bibliographic Details
Main Authors: Jing eJiang, Brooke L Fridley, Qiping eFeng, Ryan eAbo, Abra eBrisbin, Anthony eBatzler, Gregory eJenkins, Pamela eLong, Liewei eWang
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-08-01
Series:Frontiers in Genetics
Subjects:
pharmacogenomics
genome-wide association
mTOR
rapamycin
Everolimus
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00166/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fgene.2013.00166/full

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