A bovine cell line that can be infected by natural sheep scrapie prions.

Cell culture systems represent a crucial part in basic prion research; yet, cell lines that are susceptible to prions, especially to field isolated prions that were not adapted to rodents, are very rare. The purpose of this study was to identify and characterize a cell line that was susceptible to r...

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Bibliographic Details
Main Authors: Anja M Oelschlegel, Markus Geissen, Matthias Lenk, Roland Riebe, Marlies Angermann, Herman Schatzl, Martin H Groschup
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4286239?pdf=render