Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

Cell death is a critical process in health and disease, yet available markers record later stages of cell death once a cell has already begun to decompose. Here the authors show the use of a genetically encoded calcium indicator that demarcates an irreversible stage of cell death earlier than previo...

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Bibliographic Details
Main Authors: Jeremy W. Linsley, Kevan Shah, Nicholas Castello, Michelle Chan, Dominik Haddad, Zak Doric, Shijie Wang, Wiktoria Leks, Jay Mancini, Viral Oza, Ashkan Javaherian, Ken Nakamura, David Kokel, Steven Finkbeiner
Format: Article
Language:English
Published: Nature Publishing Group 2021-09-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-25549-9

Internet

https://doi.org/10.1038/s41467-021-25549-9

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