l-Citrulline improves cerebral blood flow in migraine model rats

l-Citrulline improves cerebral blood flow in migraine model rats

We have previously reported that intravenous injection of l-citrulline, an α-amino acid isolated from watermelon juice, prevented the decrease in cerebral blood flow (CBF) during cortical spreading depression (CSD) in rats, a widely accepted animal model of migraine aura. However it is not clear whe...

Full description

Bibliographic Details
Main Authors:	Yuki Kurauchi, Koichi Mokudai, Masahiko Morita, Ayako Kamimura, Asami Mori, Kenji Sakamoto, Tsutomu Nakahara, Kunio Ishii
Format:	Article
Language:	English
Published:	Elsevier 2017-11-01
Series:	Journal of Functional Foods
Subjects:	l-arginine Cerebral blood flow Cerebrovascular disorder l-citrulline Cortical spreading depression Migraine
Online Access:	http://www.sciencedirect.com/science/article/pii/S1756464617305789

Similar Items

l-Citrulline ameliorates cerebral blood flow during cortical spreading depression in rats: Involvement of nitric oxide- and prostanoids-mediated pathway
by: Yuki Kurauchi, et al.
Published: (2017-03-01)

l-Citrulline dilates rat retinal arterioles via nitric oxide- and prostaglandin-dependent pathways in vivo
by: Asami Mori, et al.
Published: (2015-04-01)

Citrulline, Biomarker of Enterocyte Functional Mass and Dietary Supplement. Metabolism, Transport, and Current Evidence for Clinical Use
by: Stefano Maric, et al.
Published: (2021-08-01)

L-Arginine and L-Citrulline Supplementation Have Different Programming Effect on Regulatory T-Cells Function of Infantile Rats
by: Yi-Chen Lee, et al.
Published: (2018-12-01)

L-Citrulline ameliorates the attenuation of acetylcholine-induced vasodilation of retinal arterioles in diabetic rats
by: Asami Mori, et al.
Published: (2021-03-01)

L-Citrulline Metabolism Orchestrates Anti-mycobacterial Immunity
by: Lange, Shannon Marie
Published: (2017)

Separation of L-arginine and L-citrulline in red and yellow crimson watermelon (Citrullus lanatus) juices extract using HPLC gradient mode
by: Adenan, M.I, et al.
Published: (2018)

Effects of L-Citrulline Supplementation and Aerobic Training on Vascular Function in Individuals with Obesity across the Lifespan
by: Anaisa Genoveva Flores-Ramírez, et al.
Published: (2021-08-01)

The Physiological Effects of Amino Acids Arginine and Citrulline: Is There a Basis for Development of a Beverage to Promote Endurance Performance? A Narrative Review of Orally Administered Supplements
by: Hollie Speer, et al.
Published: (2020-02-01)

The Role of Metabolism in Migraine Pathophysiology and Susceptibility
by: Olivia Grech, et al.
Published: (2021-05-01)

l-Citrulline Metabolism in Mice Augments CD4+ T Cell Proliferation and Cytokine Production In Vitro, and Accumulation in the Mycobacteria-Infected Lung
by: Shannon M. Lange, et al.
Published: (2017-11-01)

Dietary L-citrulline supplementation modulates nitric oxide synthesis and anti-oxidant status of laying hens during summer season
by: Victoria A. Uyanga, et al.
Published: (2020-10-01)

Arginine and Citrulline and the Immune Response in Sepsis
by: Karolina A.P. Wijnands, et al.
Published: (2015-02-01)

Advances in Migraine Mechanisms and Treatment
by: J Gordon Millichap
Published: (2004-02-01)

Nitric Oxide Deficiency in Mitochondrial Disorders: The Utility of Arginine and Citrulline
by: Mohammed Almannai, et al.
Published: (2021-08-01)

Functional Relevance of Citrulline in the Vegetative Tissues of Watermelon During Abiotic Stresses
by: Qiushuo Song, et al.
Published: (2020-05-01)

Histone citrullination: a new target for tumors
by: Dongwei Zhu, et al.
Published: (2021-06-01)

Citrulline Supplementation Improves Organ Perfusion and Arginine Availability under Conditions with Enhanced Arginase Activity
by: Karolina A.P. Wijnands, et al.
Published: (2015-06-01)

Migraine preventive drugs differentially affect cortical spreading depression in rat
by: Volodymyr Borysovych Bogdanov, et al.
Published: (2011-02-01)

Comparing markers of the nitric oxide cycle and their association with ambulatory blood pressure and end organ damage in a bi-ethnic population : a SABPA-study / Ilisma Loots
by: Loots, Ilisma
Published: (2013)

Comparing markers of the nitric oxide cycle and their association with ambulatory blood pressure and end organ damage in a bi-ethnic population : a SABPA-study / Ilisma Loots
by: Loots, Ilisma
Published: (2013)

Citrullination-Resistant LL-37 Is a Potent Antimicrobial Agent in the Inflammatory Environment High in Arginine Deiminase Activity
by: Danuta Bryzek, et al.
Published: (2020-11-01)

The use of cultured cells with defects of citrulline metabolism in diagnosis and in the study of intercellular communication
by: Davidson, James Schonland
Published: (2018)

Enhancement of fracture healing after citrulline supplementation in mice
by: DM Meesters, et al.
Published: (2020-03-01)

Migraine and neuroinflammation: the inflammasome perspective
by: Oguzhan Kursun, et al.
Published: (2021-06-01)

Acute effects of Nitrosigine® and citrulline maleate on vasodilation
by: Jeffrey M. Rogers, et al.
Published: (2020-02-01)

Citrullination of Proteins as a Specific Response Mechanism in Plants
by: Claudius Marondedze, et al.
Published: (2021-04-01)

Upregulation of IL-1 Receptor Antagonist in a Mouse Model of Migraine
by: Salvo Danilo Lombardo, et al.
Published: (2019-07-01)

Effects of L-citrulline supplementation on blood pressure: A systematic review and meta-analysis
by: Bahareh Barkhidarian, et al.
Published: (2019-01-01)

Response of laying hens to l-arginine, l-citrulline and guanidinoacetic acid supplementation in reduced protein diet
by: Hiep Thi Dao, et al.
Published: (2021-06-01)

L-Arginine Drives Macrophage Metabolism to Aid Host Defense against Mycobacterium tuberculosis
by: McKell, Melanie Catherine
Published: (2021)

L-Citrulline Supplementation Increases Plasma Nitric Oxide Levels and Reduces Arginase Activity in Patients With Type 2 Diabetes
by: Alia Shatanawi, et al.
Published: (2020-12-01)

Chemotherapy effect on arginine / citrulline cycle indicators in patients with acute myeloid leukemia and concomitant obesity.
by: H. S. Maslova, et al.
Published: (2020-07-01)

A Paradoxical Vasodilatory Nutraceutical Intervention for Prevention and Attenuation of Migraine—A Hypothetical Review
by: Devahuti Rai Chaliha, et al.
Published: (2020-08-01)

History of Migraine and Volume of Brain Infarcts: The Italian Project on Stroke at Young Age (IPSYS)
by: Valeria De Giuli, et al.
Published: (2019-09-01)

Simultaneous determination of arginine, citrulline, and asymmetric dimethylarginine in plasma by reverse-phase high-performance liquid chromatography
by: P. V. L. N Srinivasa Rao, et al.
Published: (2017-10-01)

Nitric Oxide and Peroxynitrite Imbalance Triggers Cortical Hyper-Excitability and Migraine Headaches
by: Mahmud, Farina J.
Published: (2017)

Genetic mouse models of migraine
by: Daniela Pietrobon, et al.
Published: (2019-07-01)

Gain of Function for the SCN1A/hNav1.1-L1670W Mutation Responsible for Familial Hemiplegic Migraine
by: Sandra Dhifallah, et al.
Published: (2018-07-01)

Reconstitution of T Cell Proliferation under Arginine Limitation: Activated Human T Cells Take Up Citrulline via L-Type Amino Acid Transporter 1 and Use It to Regenerate Arginine after Induction of Argininosuccinate Synthase Expression
by: Anke Werner, et al.
Published: (2017-07-01)