Toxicological Effects of Polycyclic Aromatic Hydrocarbon Quinones Contaminated in Diesel Exhaust Particles

Toxicological Effects of Polycyclic Aromatic Hydrocarbon Quinones Contaminated in Diesel Exhaust Particles

Accumulated epidemiological and animal studies have suggested that prolonged exposure to ambient particulate matter (PM) is associated with an increased risk of cardiovascular disease and pulmonary dysfunction. While diesel exhaust particles (DEP) contain large variety of compounds, polycyclic aroma...

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Bibliographic Details
Main Authors: Yoshito Kumagai, Keiko Taguchi
Format: Article
Language:English
Published: Asian Association for Atmospheric Environment 2007-12-01
Series:Asian Journal of Atmospheric Environment
Subjects:
polycyclic aromatic hydrocarbon
quinone
oxidative stress
vascular dysfunction
diesel exhaust particle
Online Access:http://asianjae.org/_common/do.php?a=full&b=11&bidx=1593&aidx=20036
Description
Summary:Accumulated epidemiological and animal studies have suggested that prolonged exposure to ambient particulate matter (PM) is associated with an increased risk of cardiovascular disease and pulmonary dysfunction. While diesel exhaust particles (DEP) contain large variety of compounds, polycyclic aromatic hydrocarbons (PAHs) are a dominant component contaminated in DEP. This article reviews effects of two PAH quinones, 9,10-phenanthraquinone (9,10-PQ) and 1,2-naphthoquinone (1,2-NQ), on vascular and respiratory systems.
ISSN:1976-6912
2287-1160

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