Efficacy and safety of direct switch to indacaterol/glycopyrronium in patients with moderate COPD: the CRYSTAL open-label randomised trial

Efficacy and safety of direct switch to indacaterol/glycopyrronium in patients with moderate COPD: the CRYSTAL open-label randomised trial

Abstract Background Dual bronchodilation combining a long-acting β2-agonist (LABA) and a long-acting muscarinic antagonist (LAMA) is the preferred choice of treatment recommended by the Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2017 guidelines for the management of patients with...

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Main Authors: Claus F. Vogelmeier, Mina Gaga, Maryam Aalamian-Mattheis, Timm Greulich, Jose M. Marin, Walter Castellani, Vincent Ninane, Stephen Lane, Xavier Nunez, Francesco Patalano, Andreas Clemens, Konstantinos Kostikas, on behalf of the CRYSTAL study investigators
Format: Article
Language:English
Published: BMC 2017-07-01
Series:Respiratory Research
Subjects:
Chronic obstructive pulmonary disease
Dual bronchodilation
Indacaterol/glycopyrronium
Direct switch
Open-label
Online Access:http://link.springer.com/article/10.1186/s12931-017-0622-x

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