Long non-coding RNA LPP-AS2 promotes glioma tumorigenesis via miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loop

Long non-coding RNA LPP-AS2 promotes glioma tumorigenesis via miR-7-5p/EGFR/PI3K/AKT/c-MYC feedback loop

Abstract Background Glioblastoma is the most common primary malignant intracranial tumor with poor clinical prognosis in adults. Accumulating evidence indicates that long non-coding RNAs (lncRNAs) function as important regulators in cancer progression, including glioblastoma. Here, we identified a n...

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Bibliographic Details
Main Authors: Xiaoming Zhang, Wanxiang Niu, Maolin Mu, Shanshan Hu, Chaoshi Niu
Format: Article
Language:English
Published: BMC 2020-09-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
lncRNA
LPP-AS2
EGFR
miR-7-5p
Glioma
PI3K/AKT/c-MYC pathway
Online Access:http://link.springer.com/article/10.1186/s13046-020-01695-8

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